Type 2 diabetes is caused by the failure of beta cells in the pancreatic islets to deliver enough insulin to maintain blood glucose levels in normal ranges. Researchers recently identified a novel cluster of dysregulated genes in the pancreatic islets of patients with type 2 diabetes. The researchers sought to identify which genes are abnormally expressed in islet beta cells in people with diabetes, compared to islet beta cells of non-diabetic people. The abnormal genes could account for beta cell failure in diabetes, and their identification could lead to future treatments. Read more