Researchers at Yale University believe targeting a protein called islet amyloid polypeptide (IAPP), a hormone made by the same cells that produce insulin, may lead to a new treatment for type 2 diabetes. The researchers say that when IAPP develops the wrong shape, it pokes holes in the membranes of pancreatic islets that are large enough to kill the insulin-secreting cells. They believe that designing a compound to target a particular IAPP structure and prevent the large holes may prevent the deterioration of islet cells that leads to type 2. Read more