Many patients with diabetes struggle with weight management, and many drugs used to treat diabetes can further contribute to weight gain. Researchers have found that the SGLT-2 inhibitors, a newer class of drugs, are very effective when combined with diet and exercise in helping patients lose weight. Researchers have found that the amount of weight loss varies among the drugs in this class: Jardiance (Empagliflozin), Forxiga (Dapagliflozin), Invokana (Canagliflozin), and ertugliflozin (Steglatro), with the average amount of weight lost highest for Canagliflozin. Read more