Drugs

Lilly Says Its New Injectible Outperforms 3 Popular Diabetes Drugs

Lilly says its once-weekly injectible drug, dulaglutide, has outperformed three other widely taken diabetes drugs in three just-concluded Phase III studies.

Intravitreal insert provides substantial long-term benefit in DME patients

Fluocinolone acetonide intravitreal inserts substantially improved visual acuity for up to 3 years in patients with diabetic macular edema, according to the FAME studies.

New insulin analog shows promise

The novel basal insulin analog LY2605541 may show advantages over insulin glargine in diabetics, according to researchers.

Drug offers new pain management therapy for diabetics

A study from the University of Calgary’s Hotchkiss Brain Institute shows there is evidence to support a new drug therapy called nabilone to treat diabetic neuropathy, or nerve pain.

Generic Actos Receives Final Approval

Watson Pharmaceuticals Inc. said Friday that it began shipping a generic version of the type 2 diabetes treatment Actos.

ViaCyte gets funding for potential diabetes cure

ViaCyte is developing a drug delivery system that enables implanted pancreatic progenitor cells to survive and differentiate into functioning insulin-producing islet cells.

Insulin Degludec Beats Sitagliptin in Type 2 Diabetes

Adding insulin degludec to an existing oral antidiabetes regimen produced significantly better glycemic control than did adding sitagliptin in the first head-to-head trial of the two drug classes in patients with type 2 diabetes.

Lilly’s dulaglutide tops 3 diabetes drugs in late-stage trials

Eli Lilly & Co’s experimental once-weekly diabetes drug dulaglutide proved superior in late-stage clinical trials to three other widely used medicines that are dosed more frequently, the company said on Monday.

Oral Agents for Lowering Blood Sugar in Type 2 Diabetes

There are currently eight categories of oral agents marketed in the US for lowering blood sugar in type 2 diabetes. Each category has different reasons for use, differing efficacies for different individuals, etc.

Glucose Control Can Blunt Aspirin Resistance

Aspirin resistance – a concern among patients with type 2 diabetes who may be at high risk of heart disease – may be attenuated by aggressive glucose-lowering therapy, researchers said here.

Type 2: Finnish Study Says Statins Users Run Higher Diabetes Risk

Recently, a Finnish study evaluated nearly 2,800 nondiabetic individuals, close to 500 of whom were using statins, after they had participated in a year of lifestyle interventions intended to improve their glucose metabolism.

Use of more costly diabetes medications varies widely

Even within an integrated Veterans Affairs (VA) system with a uniform national formulary and established criteria for drug use, there is substantial variation in the use of thiazolidinediones and long-acting insulin.

Target for Obesity Drugs Comes Into Focus

Researchers at the University of Michigan have determined how the hormone leptin, an important regulator of metabolism and body weight, interacts with a key receptor in the brain.

Statins show raised blood glucose levels in new study

In a Finnish study of nearly 3,000 people at high risk of diabetes, those taking statins had higher fasting blood glucose and triglyceride levels and a higher incidence of developing type 2 diabetes than non-statins users.

Monoclonal antibody effective therapy for diabetic retinopathy

An antibody can reduce retinal vascular leakage and inflammation in rat models of diabetic retinopathy, according to a study published online Oct. 1 in Diabetes.

Merck’s once-a-week diabetes drug effective in clinical study

An experimental once-a-week drug for type 2 diabetes being developed by Merck & Co proved effective in lowering blood sugar levels in a mid-stage clinical trial, according to data presented on Wednesday.

New Data Demonstrate Treatment With ‘Januvia’ Works for Hypoglycemia

New data announced at the 48th European Association for the Study of Diabetes (EASD) annual meeting show results of post-hoc pooled analysis of patients with type 2 diabetes aged 65 or older.

Metformin May Be Useful for More People Than Previously Thought

Metformin is an oral medicine for Type 2 diabetes that belongs to a drug class known as biguanides. It helps lower blood glucose levels by making muscle and fat cells more sensitive to insulin.

New drug can reverse type II diabetes (Video)

A new drug has been developed which is capable of halting the progression of type II diabetes in animals and actually reversing the disease.

MedicalXpress: New drug candidate in diabetes research breakthrough

CSL Limited has developed a new drug candidate that is able to prevent the development of type 2 diabetes and reverse its progression in animal models of the disease.