Medical Research

Type 1 Cured in Mice?

Researchers believe they have found a way to “trick” the body into curing type 1 diabetes. While much testing remains to be done, they are hopeful this will have a great impact on the future for people with type 1 diabetes, and perhaps have potential to address type 2 as well. Read more

Scientists Closer to Finding Genetic Cause of Type 2

Researchers at University College, London, have reported that they are closer to unlocking the genetic causes of type 2 diabetes after identifying 111 new chromosome locations, in the human genome.  Read more

Electronic Registry Can Help Predict Diabetes Outcomes

Researchers at the 2017 annual meeting of the American Association of Clinical Endocrinologists announced that using a chronic disease registry of nearly 50,000 people with diabetes helped them identify several predictors of better outcomes, including frequent visits with endocrinologists and seeing providers affiliated within the health system. Read more

Diabetes May Affect Brain Function

In a new study, patients with type 2 diabetes scored worse than the healthy controls on tests of memory and reaction times. The problem was worse in overweight diabetes patients than in those of normal weight. Read more

Does Synthetic Biology Offer a Cure for Type 1?

Type 1 diabetes requires constant vigilance. Patients with diabetes must track their blood sugar levels constantly, and calibrate insulin dosage accordingly; and even with constant management the risk of taking too much or too little insulin is always present. Can the field of synthetic biology — which incorporates computer science, engineering, and biology — offer the […]

Obesity Top Cause of Preventable Life-Years Lost

A new study says obesity resulted in up to 47 percent more life-years lost than tobacco or high blood pressure. The study looked at how behavioral risk factors contribute to causes of death among Americans. Obesity and diabetes caused the highest number of preventable life-years lost, followed by tobacco use, high blood pressure and high […]

Smartphones May Learn to Speak to Cells

Researchers have demonstrated a new system in which a smartphone is used to tell engineered cells implanted in diabetic mice to produce insulin. The closed-loop system uses a digital glucometer to transmit data on the rodents’ blood glucose levels to a smartphone. The smartphone processes the data and then signals the implanted cells to deliver insulin. […]

Victoza Tested as Add-on Therapy for DKA in Type 1

A recent study has looked into whether Victoza and other drugs in its class (GLP-1 agonists) can help people with type 1 diabetes to lower their blood glucose levels and lower risk of diabetic ketoacidosis (DKA). The study, conducted by researchers at the Diabetes and Endocrinology Center of Western New York, investigated whether Victoza could reduce production […]

Can Intestinal Bacteria Protect Against Type 2?

A new study from researchers in Finland suggests that a high concentration of indolepropionic acid in the serum protects against type 2 diabetes. Indolepropionic acid is produced by intestinal bacteria, and a diet rich in fiber can help boost its production. According to the researchers, the discovery provides additional insight into the role of intestinal […]

Type 1 Diabetes Risk May Come Down to Gut Bacteria Counts

Diabetes researchers have long noticed that labs have different rates of success breeding mice to have the equivalent of Type 1 diabetes. At first, many scientists attributed this to poor management of genetic drift in some labs, but this theory didn’t hold up. If you transferred a group of mice from a lab with a […]

Fasting Diet Regenerates Beta Cells in Mice

For years, there has been a vocal minority of Type 1 diabetes activists who have claimed that a low-calorie, low-carb diet is a great, but often ignored, treatment option for maintaining blood glucose levels with Type 1 diabetes. Now, a new study may provide strong scientific evidence that such a diet-focused treatment restores beta cell […]

Where are all the new diabetes drugs?

So has pharma run out of ideas in diabetes? Not exactly. But whether its ideas will ever get to market is another question. There’s plenty of promising science in the early stages of research. Available drugs, however, work pretty well. Given the cost of development and a high bar for approval, pharma can only afford […]

A New Combination Treatment Could Become the Standard T2 Diabetes

A study in Diabetes Care showed that patients with poorly controlled type 2 diabetes who received a combination of exenatide and pioglitazone had a threefold lower rate of hypoglycemia, a one-percentage-point greater reduction in A1C and less weight gain than those in the basal-bolus insulin therapy group.

Research on Remission of Prediabetes to Normal Glucose Tolerance in Obese Adults

This study objective was to determine the effect on remission of prediabetes with a high protein (HP) versus high carbohydrate (HC) diet, and effects on metabolic parameters, and lean and fat body mass in prediabetic, obese subjects after 6 months of dietary intervention. They recruited women and men ages 20–50 years with a BMI ≥ […]

Less shrinkage: This is your aging brain on the Mediterranean diet

New research shows that brain shrinkage is less pronounced in older folks whose diets hew closely to the traditional diet of Mediterranean peoples — including lots of fruits, vegetables, legumes, nuts and olive oil, little red meat and poultry, and regular, moderate consumption of fish and red wine.

Exercise could improve memory loss in type 2 diabetes

A link between moderate aerobic exercise and improving memory loss in people with diabetes has been found in a new study. Researchers from the University of Tsukaba in Japan found four weeks of moderate activity improved memory dysfunction in mouse models of type 2 diabetes.

What is the relationship between diabetes and cognitive decline?

People with diabetes mellitus may be at increased risk for cognitive decline. Correlating these findings with activities of daily living and with degree of DM control is needed, but this study provides further evidence that treating DM may decrease the burden of cognitive decline in older adults.

Can Statins Offset Insulin-Related Cancer Risk in T2DM?

The researchers found that the risk of cancers of the colon (males only), liver (males only), pancreas, lung (males only), and brain (males only) were increased up to nine-fold for patients treated with insulin or insulin secretagogues; the risk of prostate cancer was decreased strongly. The risks were generally decreased for patients taking statins, with […]

Diabetes In Control – How To Drop Blood Sugars By 12%

Researchers concluded that telling patients with type 2 diabetes to “Take a short walk right after meals” may be one of the best exercise prescriptions a clinician can give. Results from the randomized crossover study show that post-meal blood glucose levels dropped 12%, on average, when patients with type 2 diabetes walked for 10 minutes […]

How Your Body Temperature Can Affect Your Metabolism

As humans, we need to generate body heat to keep all of the chemical processes that run our bodies functioning. “Maintaining proper body temperature is crucial,” says Yu Hua Tseng, Ph.D., Principal Investigator in the Section on Integrative Physiology and Metabolism at Joslin Diabetes Center.