Medical Research

Nature Journal – Potential new therapeutic: Scientists find molecule to block insulin-degrading enzyme (IDE).

The study, which was published in the journal Nature, focused on the role of insulin-degrading enzyme (IDE). This enzyme helps to break down insulin, so finding a way to block its function could lead to new treatments for diabetics, the researchers speculated. In their work, the team was able to find a molecule called 6bK […]

New England Journal of Medicine – Surgical versus Medical Treatment for Obese Patients with Diabetes

Would the initially observed benefits of surgery stand the test of time? According to findings from a three-year follow-up study to STAMPEDE, also recently published in NEJM, the answer is yes. The STAMPEDE trial investigators analyzed glycated hemoglobin levels to see how well glycemic control was maintained after three years.

WebMD – Brain Changes & Type 1 Diabetes Diagnosis in Kids

A serious complication of type 1 diabetes called diabetic ketoacidosis (DKA) can cause temporary changes to the brain matter of children newly diagnosed with the disease, researchers say.

WebMD – Diabetes May Be Bigger Threat to the Female Heart: Study

The results support findings from an earlier analysis that found that women with diabetes have a nearly 50 percent increased risk of death from heart disease compared to men with diabetes, the study authors said.

Study links increasing severity of heart failure with increased risk of developing diabetes

A previous study by the same authors has shown an increased risk of diabetes in patients with heart failure following a heart attack, but this new research aimed to analyse all patients with heart failure regardless of whether or not they had had a heart attack.

BattleDiabetes – A screening tool can automatically detect diabetic retinopathy

A new computer program, however, could make it easier for doctors to spot potential problems. The scientists who created EyeAlert, a patent-pending program, explain that the program can take images of a patient’s retina. Based on the results, it will quickly offer a “refer” or “no refer” recommendation for further care.

Nature Medicine – A natural molecule discovered to treat type 2 diabetes

Researchers at the Universite Laval Faculty of Medicine, the Quebec Heart and Lung Institute Research Center, and the Institute of Nutrition and Functional Foods have discovered a natural molecule that could be used to treat insulin resistance and type 2 diabetes.

Examiner.com – Low-carb diet dramatically reduces TII diabetes inflammation: Beats low-fat diet

Researchers at Sweden’s Linköping University made the conclusion after monitoring 61 diabetic patients who were placed on either on a low-carb diet or a traditional low-fat diet.

BattleDiabetes – Exercise before meals could help stabilize blood sugar levels

Short bursts of intense exercise before eating could help people with insulin resistance normalize their blood sugar levels, according to a new small study.

BattleDiabetes – Coffee could prevent retinal damage in people with diabetes

The key ingredient responsible for this protective benefit is chlorogencic acid (CLA), a powerful antioxidant, say researchers from Cornell. The team studied mice whose eyes were treated with nitric oxide, a substance that would create oxidative stress and free radicals, thereby contributing to retinal degeneration in the eyes.

DiabetesInControl – Threshold Effects of 25-Hydroxyvitamin D on Glucose Tolerance and Insulin Resistance

A threshold level of 25-hydroxyvitamin D may exist with potential benefits on glycemic control. Vitamin D supplementation is a common practice throughout the United States. Levels of 25-hydroxyvitamin D, 25(OH)D, that are considered normal are based upon guidelines established primarily from bone metabolism studies.

ASweetLife – LADA and GAD: Diagnosing Type 1.5 Diabetes

Researchers in Germany have further endorsed the effectiveness of a blood test that helps determine whether some adult diabetics diagnosed as type 2 diabetes are actually in the early stages of having type 1 diabetes.

DiabetesInControl – Rates of Diabetic Heart Attacks and Strokes Fall 60%

Researchers examined trends in the incidence of diabetes-related complications, between 1900 and 2010. Over the past two decades, the rates of myocardial infarctions and strokes in diabetic patients has dropped by over 60% according to a recent study.

DiabetesInControl – Adequate Vitamin D Levels Linked to Normal Glucose Metabolism

A new observational study suggests that a 25-hydroxyvitamin D (vitamin D) level of about 26 ng/mL is needed for normal glucose metabolism in both black and white obese, postmenopausal women.

WebMD – Low Blood Sugar & Heartbeat in People With Diabetes

Low blood sugar levels — known as hypoglycemia — in people with diabetes may cause potentially dangerous changes in heart rate, according to a small new study.

MedicalXpress – Low blood sugar may affect heartbeat in people with diabetes

This study’s findings may help explain why a large-scale study found that very tight control of blood sugar levels in people with type 2 diabetes led to higher-than-expected death rates.

DiabetesInControl – Fatty Liver Disease Tied to Diabetes, Atherosclerosis

Non-alcoholic fatty liver disease (NAFLD) is an independent predictor of both type 2 diabetes and carotid atherosclerosis, according to two studies

MedicalXpress – Two papers on groundbreaking research into hypoglycemia detection

“While most of us perceive hypoglycemia as a nuisance which may make us feel fuzzy-headed or causes us to lose some motor control, if severe it can actually cause convulsions, coma and even death,” said Casey Donovan, professor of biological sciences at USC Dornsife.

New technique detects microscopic diabetes-related eye damage

New early-warning signs of the potential loss of sight associated with diabetes have been detected by researchers. This discovery could have far-reaching implications for the diagnosis and treatment of diabetic retinopathy, potentially impacting the care of over 25 million Americans.

BattleDiabetes – Chromium supplements don’t help lower blood sugar, new research suggests

A three-decade study from researchers at the University of Miami found that chromium supplements are not useful in lowering fasting glucose levels in either healthy individuals or those with diabetes.