Medical Research

Short-term intensive insulin rx lowers glycemic variability in early DM

Short-term intensive insulin therapy (IIT) can improve β-cell function in type 2 diabetes mellitus (T2DM) in association with decreased glycemic variability, according to a study published in the April issue of Diabetes Care.

STAMPEDE 3 Results: Bariatric Surgery vs. Intensive Medical Therapy

More than a third of patients who had Roux-en-Y gastric bypass (37.5%) achieved an HbA1c level of 6.0% after 3 years, as did 24.5% of the patients who underwent sleeve gastrectomy. That was significantly better than the 5% of medically managed patients who reached goal (P<0.001 for bypass and P=0.01 for the sleeve).

Medical Xpress – Insomnia may significantly increase stroke risk

The risk of stroke may be much higher in people with insomnia compared to those who don’t have trouble sleeping, according to new research in the American Heart Association journal Stroke.

DiabetesCare – Steamed Food Better for Insulin Sensitivity

A study found that eating foods that are steamed or boiled can help insulin work better in overweight women. Glycation end products (AGEs) are present in grilled or broiled food and they seem to contribute to insulin resistance. Participants eating the low-AGE diet had significantly greater insulin sensitivity by the study’s end.

NYT – Low Vitamin D Levels Linked to Disease in Two Big Studies

People with low vitamin D levels are more likely to die from cancer and heart disease and to suffer from other illnesses, scientists reported in two large studies published on Tuesday.

BattleDiabetes – Depression in diabetics linked to kidney disease

If you have diabetes and also suffer from depression, you may have an increased risk of developing kidney failure, a new study reports.

Gut metabolism changes—not stomach size—linked to success of vertical sleeve gastrectomy

It’s not the size of the stomach that causes weight loss after a specific type of bariatric surgery, but rather a change in the gut metabolism, say researchers from the University of Cincinnati (UC), the University of Gothenburg in Sweden and Cincinnati Children’s Hospital Medical Center.

NPR – Most U.S. Women Wouldn’t Know A Stroke If They Saw Or Felt One

A study published Wednesday in the journal Stroke finds that 1 in 5 U.S. women can’t identify a single warning sign — even though stroke is the fourth leading cause of death among Americans and the third among women, affecting roughly 55,000 more women than men each year.

Science Daily – Potential New Therapeutic Target for Controlling High Blood Sugar

Researchers showed that lipid molecules called phosphatidic acids enhance glucose production in the liver. These findings suggest that inhibiting or reducing production of phosphatidic acids may do the opposite.

Insulin Nation – Islet Therapy Gains Ground

As co-director of the Clinical Islet Transplant Program at the University of California, San Francisco (UCSF), Dr. Stock is one of the scientists on the frontline of trying to make islet therapy a viable. “We’ve been saying islet therapy is ‘right around the corner’ for quite awhile, but now it really seems to be true,” […]

NYT – Study Questions Fat and Heart Disease Link

Many of us have long been told that saturated fat, the type found in meat, butter and cheese, causes heart disease. But a large and exhaustive new analysis by a team of international scientists found no evidence that eating saturated fat increased heart attacks and other cardiac events.

NYT – Anger Can Set Off a Heart Attack

Angry enough to have a heart attack? It might actually happen. A new analysis has found that outbursts of anger can significantly increase the risk for irregular heart rhythms, angina, strokes and heart attacks.

Medical Xpress – Chronic hyperglycemia tied to worse surgical outcomes

Chronic hyperglycemia (A1C >8 percent) is associated with poor surgical outcomes, as measured by an increased hospital length of stay (LOS), according to a study published in the March issue of Diabetes Care.

MedicalXpress – Older age at onset of TI associated with lower brain connectivity

Children and adolescents older than age 8 at the onset of type 1 diabetes had weaker brain connectivity when tested later in life relative to those who had earlier ages of diagnosis, University of Pittsburgh Schools of the Health Sciences researchers discovered.

DiabetesHealth – Marijuana May Help Blood Sugar Control, Study Says

Marijuana actually appears to have metabolic benefits. A study published last summer in The American Journal of Medicine looked at more than 4,500 adults, of whom 579 were using marijuana at the time. That subgroup had notably better fasting blood glucose levels, insulin resistance, and waist circumference.

A1C Is a Predictor of Clinical Outcomes Following Noncardiac Surgery

Researchers discover that preoperative A1C is related to length of stay in the hospital following noncardiac surgeries.

Forbes – Heart Failure: The Missing 800 Pound Gorilla In Diabetes Trials

It was long believed that by virtue of their glucose-lowering properties diabetes drugs would confer substantial cardiovascular benefits. Now, however, that belief is no longer widely held and the FDA now requires cardiovascular outcome trials for new diabetes drugs.

Joslin Diabetes – The Impact of Type 2 Diabetes Medications on Weight

This post is written by Osama Hamdy, M.D.,Medical Director, Obesity Clinical Program, Director of Inpatient Diabetes Management at Joslin Diabetes Center, Assistant Professor of Medicine at Harvard Medical School.

Diabetes Adds to Cancer Mortality Risk

Mortality rates are higher for cancer patients who have diabetes than those without the blood sugar disorder, Danish researchers found.

US News – Elderly Diabetes Patients on Insulin Most Vulnerable to Low-Blood-Sugar Trouble

A new look at diabetes patients in the United States who use insulin and wind up in the emergency room with low blood sugar shows the dangerous scenario is more than twice as likely to happen to those over 80 years old.