Medical Research

DiabetesHealth – Rare Mutation Destroys Gene Associated With Type 2

A recent New York Times article reports that researchers have found a rare mutation that reduces the risk of developing type 2 diabetes by two thirds, even in obese people.

Huffpost – New Clues To Why Traffic Pollution Is So Bad For The Heart

Researchers from the University of Washington Medical Center found that traffic pollution seems to affect the structure and functioning of the heart’s right ventricle.

CNN – Middle-aged? Put down the meat

Eating a high-protein diet in middle age could increase your risk of diabetes and cancer, according to a study published this week in the journal Cell Metabolism. But don’t stay away from meat for too long – the same study showed those over 65 need more protein to reduce their mortality risk.

DiabetesHealth – Life-Prolonging Chemical Could Someday Lead to Type 2 Treatment

A recent article in Scientific American discusses a synthetic chemical that has extended the lifespan of lab mice by mimicking the effects of a low-calorie diet.

Diabetes Self-Management – Oral Insulin Study for Those at Risk of Type 1

Do you have Type 1 diabetes? If so, your relatives may be interested in an actively recruiting TrialNet study that is testing whether oral insulin can prevent or delay the development of Type 1 in people who are at increased risk of the condition.

BPA linked to prostate cancer, study shows

Findings by Cincinnati Cancer Center researchers show that levels of bisphenol A (BPA) in men’s urine could be a marker of prostate cancer and that low levels of BPA exposure can cause cellular changes in both non-malignant and malignant prostate cells.

NYT – Rare Mutation Kills Off Gene Responsible for TII Diabetes

A new study based on genetic testing of 150,000 people has found a rare mutation that protects even fat people from getting Type 2 diabetes. The effect is so pronounced — the mutation reduces risk by two-thirds — that it provides a promising new target for developing a drug to mimic the mutation’s effect.

Examiner – Drinking coffee can reduce damaging inflammation in the body

Drinking coffee just might be good for you, according to some recent studies. Coffee contains substances such as polyphenols and anti-oxidants that may decrease not only the effects of aging but also reduce the inflammation that contributes to many diseases.

DiabetesInControl – Effectiveness of Metformin in Protection against Bladder Cancer

This study was conducted using data from The Health Improvement Network (THIN), an electronic medical records database used in the UK. The database contains information for >10 million patients, making it ideal for rarer outcomes such as bladder cancer.

DiabetesInControl – HbA1c and Glucose Targets May Be Unaligned

A new analysis of continuous glucose monitoring suggests that the current A1c and glucose level recommendations for patients with diabetes are not in sync.

DiabetesHealth – Bariatric Surgery Shows Significant Effect on Obese Type 1s

Here’s a development to keep your eye on: Bariatric surgery performed on a small group of morbidly obese type 1s led to considerable weight loss, improved glycemic control, and improved metabolic profiles up to three years later.

DiabetesHealth – Weekly Type 2 Drug to Be Delivered Via Needle Patch

A recent agreement between Zosano Pharma, Inc. and Novo Nordisk could lead to the introduction of a once-weekly drug for type 2s that is administered via a micro-needle patch system.

NYT – Sleep Apnea May Worsen TII Diabetes

Sleep apnea can worsen blood sugar control in people with Type 2 diabetes by disrupting the deepest stage of sleep, a new study suggests. The findings provide another good reason for people with sleep apnea to wear a CPAP mask that helps assure uninterrupted breathing, the standard treatment for the condition, throughout the night.

DiabetesInControl – More Evidence Memory Problems Linked to High Blood Sugar

A recent study found that short and long term high blood sugars appear to affect memory negatively. Researchers looked at fasting blood glucose and hemoglobin A1c and established that both were connected to reduced performance on memory tests.

Diabetes Self-Management – New study: Weight and TII Diabetes

n the popular imagination, Type 2 diabetes is often associated with being overweight or obese. According to a study released last week, however, while there is a correlation between overweight and diabetes, the pattern may be more complex than even many scientists had previously believed.

Diabetes Mine – Islet Transplantation: On the Verge of Mainstream?

As someone who’s been doing islet cell transplants for 20-plus years now, Dr. Jose Oberholzer in Chicago wonders why more people with diabetes don’t know about the procedure as an option.

Type 1 Diabetes: A treatment’s in sight but where’s the funding?

Preparing for human clinical trials, the research pediatrician at Children’s Hospital of UPMC of Pittsburgh needs $7 million to $10 million for a multi-site trial involving 105 people with a recent diagnosis of type 1 diabetes. But federal budget cuts are making it difficult to land research grants through the National Institutes of Health.

US News – British Experimental ‘Implanted Insulin’ Device Seeks to Control Blood Sugar Levels

The device, which is currently dubbed “a self-regulating insulin delivery device,” would be implanted in the abdomen. The outside of the device would be made of plastic or metal and there would be no electronic or moving parts.

JDRF and ViaCyte to move encapsulated cell therapy into clinical development for TI’s

ViaCyte’s VC-01 product candidate is a cell replacement therapy that could transform the way individuals with type 1 diabetes manage their disease by supplying an alternative source of insulin-producing cells with the potential to free individuals from a dependence on external insulin use.

Type 2 Diabetes Risk Lowered with Magnesium Intake

Studies have shown that those with higher magnesium intake are 10-47% less likely to develop type 2 diabetes. In the U.S., however, only about 50% of the population achieve the recommended dietary allowance of magnesium, which is 400-420 mg/day for men and 300-310 mg/day for women.