Studies of diabetes drugs empagliflozin and dapagliflozin, both in the SGLT-2 inhibitor class, have shown they help reduce cardiovascular risk for diabetes patients. Now, researchers have found that empagliflozin is beneficial for the heart in people without diabetes as well. Read more
A clinical trial of a new stem cell-derived pancreatic islet cell treatment for type 1 diabetes, by Vertex Pharmaceuticals, is moving forward. According to Vertex, the therapy, called VX-880, has the potential to restore the body’s ability to normalize blood glucose levels through restoration of pancreatic islet cell function. Read more
Type 2 diabetes is the condition that results when β-cells (beta cells) cannot release enough insulin for the body’s needs. A group of researchers say they have new insight into how “weak” beta cells bond with other, more mature cells to boost insulin production, which can help us understand more about the processes that lead […]
Researchers have discovered a new insulin inhibitory receptor, named inceptor. (Insulin receptors are areas in human cells that allow insulin in the blood to join or bind with the cell.) The researchers found that blocking inceptor function makes the insulin signaling pathway in pancreatic beta cells more sensitive, which could potentially allow protection and regeneration […]
Prediabetes is the term for the condition when blood sugar levels are consistently high, but the patient has not yet developed full-blown type 2 diabetes. People with prediabetes are often treated with lifestyle changes such as diet and exercise, and sometimes with medication. However, a team of researchers now say that there are in fact […]
Dexamethasone, a steroid being used to treat severe cases of COVID-19, is less effective in treating the coronavirus in people who have diabetes and other risk factors, researchers say. Dexamethasone suppresses the immune system, thus alleviating the damage done to the lungs in patients with an overactive, potentially deadly immune response. Read more
Researchers studied the relationship between COVID-19 and patients with diabetes in order to assign a point system to chronic risk factors that can affect COVID-19 cases, including diabetes, obesity, and cardiometabolic disease. Their scoring system can be used to predict the link between COVID, diabetes, and the risk of deaths. Read more
The immune system fights against dangers like bacteria, viruses, and various other pathogens using a variety of “T cells.” Researchers have engineered a particular type of T cell, called 5MCAR T cells, which they say completely eliminated harmful T cells that invaded the pancreas. These 5MCAR T cells could potentially be used to fight diabetes […]
Knee osteoarthritis, diabetes, and cardiovascular disease are all conditions that are common in older individuals, and frequently coexist with each other. In addition to aging, osteoarthritis is also associated with cardiovascular risk factor like diabetes, hypertension, and obesity. Read more
High blood sugar levels are correlated with COVID-19 mortality, even in people with no history of diabetes, according to new research. Because of this, early blood glucose screenings in people who contract COVID-19 are needed, the researchers say. Read more
A new treatment called endoscopic duodenal mucosal resurfacing (DMR), combined with a glucagon-like peptide (GLP)-1 receptor agonist medication, has been shown to improve glycemic control in patients with type 2 diabetes, and possibly could enable them to discontinue insulin therapy. Read more
Research conducted by the University of South Australia, the China Medical University, and Qatar University says that too much egg consumption can increase your risk of diabetes. The researchers used data from 1991 to 2009 to assess egg consumption in a large number of Chinese adults, and found that people who regularly consumed one or […]
Researchers say that low levels of a protein, pregnancy-associated plasma protein A (PAPPA), that is commonly seen in screening tests for chromosomal disorders in the first trimester of pregnancy is associated with adipose tissue remodeling, glucose resistance and gestational diabetes mellitus in pregnant women. The protein levels could potentially be used as both a diagnostic […]
People with diabetes or high blood pressure who contract COVID-19 may be at greater risk of developing neurological complications such as bleeding in the brain and stroke, according to an ongoing study. Read more
Obesity and diabetes are both risk factors for pancreatic cancer. Bariatric surgery, a.k.a. weight loss surgery, significantly reduced the risk for pancreatic cancer in patients with obesity and diabetes, according to a recent study. Read more
A precision medicine treatment has led to the reversal of a case of type 1 diabetes in a male patient, says a study published in the New England Journal of Medicine. The researchers found the patient had a harmful mutation in a gene called STAT1, and treated the patient with a drug that could inhibit […]
Testing HbA1c levels — a standard test to diagnose diabetes — can accurately predict cardiovascular risks and successfully indicate cardiovascular disease, researchers say. Read more
Insulin may have reached an evolutionary dead end, a group of scientists say. This means that insulin’s ability to adapt to obesity is limited, which renders most people vulnerable to type 2 diabetes. Read more
A type of wrinkled “super pea” could potentially help control blood sugar levels and thus reduce the risk of type 2 diabetes, according to researchers from the Imperial College London, the John Innes Centre, Quadram Institute Bioscience and University of Glasgow, UK. The researchers suggest incorporating the peas into foods, whether as whole pea seeds […]
A small trial found that an endoscopic therapeutic procedure, which involved putting a small balloon filled with hot water down the patient’s throat, successfully reduced the need for insulin use in most participants. The procedure burns away some of the small intestine’s surface cells which are then replaced; the new cells signal the body to […]