Medical Research

FDA: GLP-1 inhibitors Diabetes Drugs Not Linked to Pancreatic Cancer

In yet another boost to several large drugmakers, the FDA has agreed with European regulators there is no existing evidence to confirm recent concerns that a widely used group of diabetes drugs called GLP-1 inhibitors is linked to pancreatic cancer, an FDA spokeswoman says.

Fox News – Diabetes drug Merformin may increase life span

Mice that were fed the drug, called metformin lived about 5 percent longer than those that were not fed the drug. The treated mice lived 160 weeks, while those not taking the drug lived about 150weeks.

ScienceBlog – Why type 2 diabetes sometimes disappears after gastric bypass surgery

A research team led by Nicholas Stylopoulos, HMS assistant professor of pediatrics at Boston Children’s Hospital, has identified the small intestine—widely believed to be a passive organ—as the major contributor to the body’s metabolism, based on a study in rats. The report appears in the July 26, 2013, issue of Science.

Clinical Endocrinology – Statins for low CVD risk? Check glucose first

Statin therapy in individuals who had a low risk of cardiovascular disease was not cost effective when the therapy’s potential to increase the risk of diabetes was taken into account, according to an analysis by researchers at the Centers for Disease Control and Prevention.

Medical News Today – How Botox works could reveal diabetes secrets

Understanding the proteins that are targeted by the cosmetic drug Botox (onabotulinumtoxinA) could lead to breakthroughs against type 2 diabetes, according to researchers at Heriot-Watt University in Scotland.

BattleDiabetes.com – Skipping breakfast and late-night snacking can raise risk for heart disease

Men who skip breakfast or indulge in late-night cravings might be more at risk for a heart attack and coronary heart disease, according to a new study published in the journal Circulation.

DiabetesMine – Once-a-Week Injection Could Fight Diabetes Complications

What if a once-a-week injection could stave off long-term diabetes complications like nerve, kidney and eye damage? And what if that shot, not too different than giving yourself a dose of insulin, was something you could have done in a routine doctor’s visit at the same time they’re measuring blood pressure, cholesterol, and other in-office […]

Medical News Today – People with diabetes have at least 50% increased risk of physical disability

Previous studies examining the risk of disability associated with diabetes have produced varying results, ranging from no association, to a doubling of risk. The new study is the first meta-analysis to pool estimates taken from earlier studies, providing a more reliable estimate of the likely risk of disability associated with diabetes.

medGadget – Glucose Sensing Sponge Delivers Insulin Precisely When and Where Needed

Now a collaboration between North Carolina State University, University of North Carolina at Chapel Hill, MIT, and Boston Children’s Hospital has developed and is analyzing a new material that can encapsulate insulin and release it as needed into the blood stream.

ScienceDaily – Could Turning On a Gene Prevent TII Diabetes?

The resistance to insulin seen in type 2 diabetics is caused partly by the lack of a protein that has not previously been associated with diabetes. This breakthrough could potentially help to prevent diabetes.

Type 1’s with Type A Personalities Live Longer

Researchers analyzed data from the CDC, which has followed a cohort of patients with type 1 diabetes for 22 years.

Estrogen Therapy Can Save Lives, According to Study

Now, a new study out of Yale School of Medicine suggests anywhere from 18,000 to 91,000 women in their 50s who had hysterectomies may have died prematurely in the last decade because they did not take estrogen-only hormone replacement therapy.

Impaired Glucose Tolerance (Pre-diabetes) Can Lead To Cognitive Dysfunction

People with impaired glucose tolerance – the precursor to Type 2 diabetes – often show impaired cognitive function that may be alleviated through a diet designed specifically for their condition

Low melatonin levels linked to diabetes in women

The hormone linked to sleep regulation, melatonin plays an important role in maintaining the body’s natural rhythms. Receptors for melatonin are found all over the body, including the pancreas, suggesting that it might have the ability to impact insulin production.

WebMD – Diabetes Drug May Protect the Brain

The diabetes drug metformin may do more than help control blood sugar levels: New research suggests it may also reduce the risk of dementia. Study found patients taking metformin were 20 percent less likely to develop dementia

Diabetes In Control – When Should Screening Be Done for Visual Loss?

A 2-year screening interval for people with no sight-threatening diabetic retinopathy at diagnosis may be safely adopted. For patients with pre-existing diabetic retinopathy, a shorter interval of ≤ 1 year is warranted

Undiagnosed Pre-Diabetes Highly Prevalent in Early Alzheimer’s Disease Study

R. Scott Turner, MD, PhD, began enrolling people with mild to moderate Alzheimer’s disease into a nationwide study last year. Turner says he was “shocked” by how many study participants were found to have pre-diabetes.

DNA abnormalities may contribute to cancer risk in people with type 2 diabetes

People with type 2 diabetes are already known to have a higher risk of cancers, especially blood cancers like lymphoma and leukaemia. The new study, led by scientists at Imperial College London and CNRS in France, suggests that mutations called clonal mosaic events (CMEs) may partly explain why this is.

Type A Behavior Related to Lower Mortality Risk in Diabetes

Patients with type 1 diabetes and type A behaviors had a significantly lower mortality risk during 22 years of follow-up, investigators reported.

Science Daily – The Dark Side of Artificial Sweeteners: Expert Reviews Negative Impact

An opinion article published by Cell Press on July 10th in the journal Trends in Endocrinology & Metabolism reviews surprising evidence on the negative impact of artificial sweeteners on health, raising red flags about all sweeteners — even those that don’t have any calories.