Six U.S. research institutions are launching a multicenter network, the Diabetic Foot Consortium (DFC), funded by the National Institutes of Health, to study diabetic foot ulcers. Foot ulcers are a common diabetes complication and the leading cause of lower limb amputations in the U.S., and this is the first research network dedicated to studying how […]
Researchers have found a strong association between early episodes of poor blood sugar control, epigenetic changes (which affect the activity of particular genes without altering their DNA sequences), and diabetic complications years later, even if patients subsequently had better glycemic control. Read more
A large study of people with type 2 diabetes who had gastric bypass surgery found that their risks for all-cause mortality, cardiovascular disease, acute myocardial infarction, and congestive heart failure were all lower after the surgery. They also had reduced risk of kidney disease, hyperglycemia, cancer, and leg amputations. However, there were also some negative […]
A new study has found passive stretching helps improve blood flow, making it easier for your arteries to dilate and decreasing their stiffness. These findings could have implications for diseases like diabetes and heart disease that involve impaired vascular systems. Read more
Teplizumab may become the first antibody commercially available that can halt or delay the progression of type 1 diabetes. Researchers have found that a single 14-day infusion of teplizumab leads to a median 3-year delay in type 1 diabetes onset in high-risk individuals. Read more
Blood glucose control among youth with diabetes has not improved since 2002 levels, and has actually gotten worse in some subgroups, according to data presented at the virtual American Diabetes Association (ADA) 2020 Scientific Sessions. This is despite increased availability of diabetes technology and new therapies in recent decades, and despite more aggressive recommended blood […]
Diabetic retinopathy, a common complication of diabetes, is a major cause of blindness in adults. A new study found that visual function in diabetic mice was significantly improved after treatment with a single dose of visual chromophore 9-cis-retinal, a vitamin A analog that can form a visual pigment in the retina cells, thereby producing a […]
Black Americans must be recruited more actively for clinical trial participation, a researcher urges. Data from diabetes clinical trials show that findings often do not apply to blacks and other ethnic minorities in the same way they do to white diabetes patients. Read more
A new study investigated whether being born prematurely can raise a person’s risks of developing either type 1 or type 2 diabetes from childhood into early to mid-adulthood. Read more
Both men and women are affected by diabetes, but previous studies have found that women are more affected by macrovascular complications such as coronary artery disease and stroke. It’s not yet known why this is, but the different ways male and female bodies store fat may play a role. Read more
Obesity is a risk factor for many conditions, including type 2 diabetes. Now researchers say obesity may be a result of an alteration in the hypothalamic-pituitary-adrenal (HPA) axis. A recent study examined cortisol levels in people with obesity to determine if there is an association with diabetes, hypertension, and cortisol. Read more
The results of a recent study strengthen the theory that HbA1c is associated with coronary atherosclerosis development, a forerunner of heart disease, in people who do not have diabetes. Mixed patterned plaques were found to be more associated with higher HbA1c levels. Read more
Scientists at Washington University announced they have developed a way to use gene editing system CRISPR-Cas9 to edit a mutation certain stem cells and then turn them into beta cells that produce insulin. When transplanted into mice, the cells reversed preexisting diabetes. Read more
Previous studies have had conflicting results on whether patients with familial combined hyperlipidemia (FCHL) — a form of dyslipidemia that results in abnormally high levels of lipids — had a higher incidence of type 2 diabetes. Now a 15-year study has found patients with FCHL are a significantly higher risk for developing type 2 diabetes. […]
Exposure to air pollution alters gut microbiome composition, which subsequently increases the risk of obesity, diabetes, and other chronic illnesses, according to a new study which used whole-genome sequencing to examine whether air pollutants affected the gut microbiome of 101 young adults. Read more
Converted human stem cells cured mice with diabetes for at least nine months and, in some cases for a year. The transformed cells produced insulin, allowing the mice to decrease their high blood sugars. While the research is still in early stages, the researchers feel it holds promise. Read more
New research has found that children diagnosed with type 1 diabetes under the age of seven have a different type (specifically “endotype”) of the condition compared to patients with diabetes who have been diagnosed at age thirteen or above. These findings could spur further research into whether dormant insulin-producing cells can be reactivated. Read more
Bariatric surgery has been increasingly used in patients with obesity, and is an effective way to help aid glycemic control. It has been suggested that changing how nutrients are presented to the duodenum is one reason why improvements are seen after bariatric surgery. Importantly, this alteration does not appear to lead to malabsorption of nutrients. […]
Researchers have made progress in developing a smart insulin-delivery patch that may one day monitor and manage glucose levels in people with diabetes, and deliver the necessary insulin dosage. The adhesive patch is about the size of a quarter, is simple to manufacture, and is intended for once-a-day use. Read more
In a pair of related studies, researchers at Yale have found a potential way to reverse type-2 diabetes and liver fibrosis in mice, and have shown that the underlying processes could also be effective in people. Read more