Type 1 diabetes can potentially increase the risk of miscarriage in some circumstances, and the hormonal changes surrounding a pregnancy ended due to miscarriage or abortion can also impact type 1 management. Read more
The American Diabetes Association (ADA) recommends lowering the target hemoglobin A1C (HbA1C) guidelines for children with type 1 diabetes. This is due to the finding that chronically high blood glucose levels in children could lead to higher risk of several serious effects, including abnormal brain development and cardiac issues. Read more
Both genetic and environmental risk factors play a vital role in whether a person develops type 1 diabetes. A study looked at the impact of modifiable risk factors, such as obesity, in people who had high genetic risk for type 1. Read more
The FDA has granted fast track designation to VX-880, which is a human stem cell-derived therapy for patients with type 1 diabetes. This islet cell therapy is designed to regulate glucose levels by restoring a patient’s pancreatic islet cell function, including insulin production. Read more
Researchers are investigating a potential “inverse vaccine” for type 1 diabetes. This vaccine would use the body’s anti-inflammatory dendritic cells to retrain the immune system be less damaging to insulin-producing beta cells. If successful, this could be administered to patients in the early stages of type 1 to slow the disease’s progression. Read more
The possible role of Vitamin D levels contributing to diabetes risk has been much discussed. A recent study has found that deficiencies in Vitamin D are not linked to an increased risk of developing type 1 diabetes in Europeans. Read more
Technology has changed managing type 1 diabetes dramatically over the last 20 years, for both children and adults. Good glucose management is key to preventing many complications of diabetes, and this has been made much easier with the use of continuous glucose monitors, new pump designs, and closed-loop systems. Read more
A clinical trial of a new stem cell-derived pancreatic islet cell treatment for type 1 diabetes, by Vertex Pharmaceuticals, is moving forward. According to Vertex, the therapy, called VX-880, has the potential to restore the body’s ability to normalize blood glucose levels through restoration of pancreatic islet cell function. Read more
Eli Lilly is expanding its existing type 1 diabetes partnership with Life for a Child, with the goal of supporting more than six times as many children in the next 10 years. Lilly plans to expand care to 150,000 young people with diabetes over the next decade, providing free medicine and equipment like reusable pens […]
Metabolic syndrome is the term for a group of risk factors (including abdominal obesity, high triglycerides, and high blood pressure) that have often been discussed in terms of increasing a person’s risk for type 2 diabetes. However, researchers say metabolic syndrome also poses risks for people with type 1, increasing their risk for serious complications […]
Researchers have discovered a new insulin inhibitory receptor, named inceptor. (Insulin receptors are areas in human cells that allow insulin in the blood to join or bind with the cell.) The researchers found that blocking inceptor function makes the insulin signaling pathway in pancreatic beta cells more sensitive, which could potentially allow protection and regeneration […]
It’s been known since the early days of the pandemic that having diabetes increases the risk for severe COVID-19 complications. There are multiple factors that make the combination of diabetes and COVID-19 so serious. Some patients experience an increase in insulin resistance that raises blood glucose levels; plus, COVID-19 is sometimes treated with steroids, and […]
New studies have investigated a once-daily pill that can optimize insulin therapy and reduce HbA1c among adults with type 1 diabetes. The pill, a novel liver-selective glucokinase activator, also known as TTP399, showed superior A1c reduction compared to placebo. Read more
People with both type 1 and type 2 diabetes are at similar risk for increased COVID-19 severity, new findings conclude. Therefore, people with either type of diabetes should be prioritized in receiving COVID-19 vaccinations, researchers say. Read more
Metabolic syndrome is a group of risk factors that increase a person’s chances of developing type 2 diabetes and heart disease, including abdominal obesity, high triglycerides, low HDL cholesterol, high blood pressure, and high fasting glucose. Researchers say that people with type 1 diabetes and metabolic system are at greater risk of complications like heart […]
An artificial pancreas, also known as a closed-loop system of insulin delivery or an automated insulin delivery system, could potentially improve outcomes and quality of life in children with type 1 diabetes. Currently, less than 20% of children with type 1 diabetes attain the target glycated hemoglobin level of less than 7% that is recommended […]
The Omnipod 5 Horizon System is a hybrid closed loop automated insulin delivery device. It works with a mobile phone or personal diabetes manager. A unique feature of the device is that it uses custom-built glucose control, modifiable based on the time of day; it can also prevent the patient from experiencing a hypoglycemia episode. […]
Two large studies say that the risk of serious diabetes complications isn’t merely driven by an individual’s blood sugar control. Instead, multiple factors, which can include body mass index (BMI), age, gender, and socio-economic factors like income level, insurance coverage and education can affect a person’s risk of developing complications like diabetic neuropathy and cardiac […]
Golimumab is a human antibody that is used as an immunosuppressive drug (brand name Simponi) and is approved for the treatment of several autoimmune conditions, including ulcerative colitis. Researchers investigated whether golimumab could preserve beta-cell function in young people newly diagnosed with type 1 diabetes. Read more
Young children with type 1 diabetes often have greater insulin variability than do adults, which can lead to more complications and quality of life issues. Researchers investigated whether hybrid closed-loop devices, which deliver insulin automatically by using an algorithm that sensors glucose values in real-time, can help. Read more