In recent years, there have been warnings for the use of SGLT-2 Inhibitors that suggest an increased risk of fracture, particularly when placed on one SGLT2 inhibitor, canagliflozin (Invokana). In 2015, the US FDA added a warning on canagliflozin, indicating that patients on canagliflozin must use caution because of a fracture risk associated with the […]
Children who have had an episode of acute pancreatitis may have an increased risk for developing type 2 diabetes before the age of 40, researchers say. Read more
Serious influenza complications can result in a higher risk of hospitalization, and also mortality, in patients with diabetes. The influenza virus, commonly known as the flu, has the potential of exacerbating chronic health problems that lead to worsening the disease state of diabetes. Read more
The TTT-1 trial will begin in Scotland early in 2020 to assess a new combination therapy using insulin, dapagliflozin, and semaglutide. It is being led by Dr John Petrie from the University of Glasgow, a leading expert in the treatment of type 1 diabetes. The trial hopes the treatment will become a new option for […]
The circadian clocks inside the body’s cells that help regulate timing of many body functions and control cardiovascular disease risks within a 24-hour day appear to be affected by high glucose in obesity. “We know that high glucose impairs circadian clock functions, but now we want to know [if] by fixing the clock can we […]
The World Health Organization (WHO) has announced a plan to lower the “overly expensive” price of insulin. The agency, which is part of the United Nations, wants other drug companies to produce generic versions of insulin, which it will then test. Since its discovery in 1923, the price of insulin has risen in the United […]
Qternmet XR is a single, once daily oral tablet made of dapagliflozin, saxagliptin, and metformin. Results show that the combination of dapagliflozin and saxagliptin have improved glycemic outcomes when added to metformin in patients with diabetes as compared to either drug alone added to metformin. Adverse effects are similar to those of the individual medications. […]
To save patients with a severe form of type 1 diabetes, pancreatic cell transplantation is a “last resort” treatment, because the process is long and complex, and many of the grafted cells die quickly. Researchers have found that adding amniotic epithelial cells to these cell clusters creates much more robust “super-islets” of Langerhans. Once transplanted, […]
When you have diabetes, whether there is a “best” time of day to exercise can depend on many things — whether you’re trying to lose weight or manage glucose; whether or not you take insulin; what kind of physical activity you’re doing, and many more. Diabetes exercise expert Dr. Sheri Colberg gives her insight into […]
Researchers may be only beginning to understand how Alzheimer’s disease and type 2 diabetes could be linked. Deciphering the connection could lead to earlier Alzheimer’s diagnosis and better treatments for both diseases. The connection involves how the brain metabolizes blood sugar and the factors that influence that process, including diet, sleep, and cardiovascular health. […]
Oral semaglutide, brand name Rybelsus, is the first GLP-1 agonist that can be taken by mouth rather than requiring an injection. Studies have shown a significant reduction in A1c, a reduction in cardiovascular disease, and a reduction in weight, without the risk of hypoglycemia, for this drug. Patients must carefully follow instructions for taking the […]
A new study looked at a particular type of artificial pancreas, or closed-loop control, called the Control-IQ system — a new type of artificial pancreas that uses algorithms to adjust insulin doses automatically throughout the day. When the monitor detects that a person needs insulin, a pump releases it into the body. Read more
The FDA has approved a new treatment of Invokana for diabetic chronic kidney disease (CKD), which affects one in three patients with type 2 diabetes. CKD increases the risk for serious cardiovascular events and end-stage renal disease in patiens with type 2 diabetes. The approval of Invokana meets a 20 year need for therapy to […]
Fingerstick tests of blood sugar levels can tell patients what their blood sugar level is at any given moment, but not how consistent that level may be. CGMs can take nearly 300 blood sugar measurements a day, thus providing a new standard for measuring blood sugar control: time in range. Time in range refers to […]
Metabolic syndrome (MetS) is a set of interconnected biochemical, clinical, and metabolic factors that increase risk of heart disease and type 2 diabetes. Characteristics of MetS include high blood pressure, high blood glucose, and excess body fat around the waist. Carbohydrate intake stimulates insulin secretion, which in turn stimulates fat storage, is linked to MetS. […]
Adults with type 1 diabetes who use cannabis products are more than twice as likely to develop diabetic ketoacidosis as non-cannabis users with type 1, according to a recent study. The researchers say increased appetite due to cannabis use may be a factor, along with impaired ability to manage diabetes. Read more
Currently there is no clear consensus on dietary recommendations for pregnant women with high metabolic risks for gestational diabetes and other complications. New research puts the Mediterranean style diet to the test to evaluate the effectiveness of the diet in pregnant women. Read more
People who have diabetes or metabolic syndrome (a group of risk factors that often precedes diabetes) are at almost double the risk for developing dementia. One possible cause, the way the brain metabolizes sugar, is now being explored by researchers. Read more
The FDA has approved a new treatment of the diabetes drug Invokana for diabetic kidney disease, which affects one in three patients with type 2 diabetes and increases the risk for serious cardiovascular issues and kidney failure. Read more
Nearly one half of all children who develop type 1 diabetes are only diagnosed when they are hospitalized with a diabetic coma. Researchers are trying to see if a genetic test can detect type 1 before these emergencies occur. Read more